Dogma is a funny word to appear so prominently in a science like biology. Any picture, any model, any theory currently in vogue is resting on the shifting sands of biological weirdness. I love, for instance, the fact that the Nobel Prize in medicine this year was awarded for major form of genetic regulation that nobody knew existed eight years ago.
A few weeks ago after I posted a link to some lovely molecular biology animations, my good friend Mike Onken made a comment that contained an oblique but cutting reference to the so-called Central Dogma of molecular biology. Since Mike is a certified Level 50 Molecular Biology Warlock at Washington University in St. Louis, I knew there was a good story behind that remark. I hounded him until he gave it up. “Everybody loves the Central Dogma,” I intoned. “It’s so dogmatic, and quasi-religious certainty is very sexy these days. What have you got against it?”
I got the response I was looking for, which I happily share below. Please allow me to present the words of Mike Onken:
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