Funny gene names

Do you suppose, if your house was knocked over by Hurricane Fifi, that you might feel more slighted than if the same damage had been done by a storm with a more muscular name? Generals have long understood the value of giving their military operations intimidating names like Rolling Thunder and Urgent Fury. If you have a rare disease, it can be a source of perverse comfort to know that it is named after a pair of stern and bespectacled Old World doctors like Creutzfeldt and Jakob or Kugelberger and Welander.

But geneticists and molecular biologists have a couple of strikes against them when it comes to naming genes. First of all, they tend to name genes for what happens when the gene doesn’t work, which ends up making a critical functionality sound like a problem. Thus eyeless helps make eyes. The other problem is that it never occurred to them that the silly inside-joke names they gave to their fruitfly genes would have such straightforward parallels in humans. As it says in the NY Times article ‘Sonic Hedgehog’ Sounded Funny, at First:

It’s a cute name when you have stupid flies and you call it a ‘turnip.’ … When it’s linked to development in humans, it’s not so cute any more.

I came across a link to the Times article because of an entertaining blog post from the bioinformaticist Nick Saunders: What’s in a (gene) name? . You never know when a name is going to matter.

Tom Lehrer, lost and found

On the subject of libraries, Boswell quotes Samuel Johnson thus: “Knowledge is of two kinds. We know a subject ourselves, or we know where we can find information on it.”

What would Johnson make of the web? I think about this quote whenever I reflect on the fact that, to a fair approximation, all human knowledge is one Google search away. In other words, knowledge is of two kinds: that which we know, and that which we have the good sense to ask Google for. More succinctly, obscurity ain’t what it used to be. Obscurity is not the obscurity of the dusty book lost in the shadowy stacks. Obscurity is the obscurity of your inability to formulate a question in the first place. Once you can do that, there is no question about where to look.

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This leads to a surprising conclusion. The more convenient the search, the more valuable the intrinsic knowledge. The distance between forming the question and finding the answer is vanishing. So relatively speaking, packing a lot of information into your head still pays. Take heart… that liberal arts education may pay off yet!

This all came to mind because of Tom Lehrer and my brother-in-law Joe. Joe sent me a link to some YouTube videos of Tom Lehrer performing songs of his that I know far too well. Did I want to see them? Of course I wanted to see them! I don’t know why it didn’t occur to me to go looking for them before. Joe’s email nudged them “closer” to me, but really they were the same distance from me all along. Everything I want to know is right there, only I don’t yet know that I want to know it yet.

Enough. Now go watch Poisoning Pigeons in the Park.

Thanks Joe!

Six Degrees Could Melt the World

As long as we’re talking about environmentalism and eco-tainment, I watched some of Six Degrees Could Change the World on the National Geographic Channel tonight (I sure do watch a lot more National Geographic and Discovery programming since I got a high-definition TV). The show is all about the dramatic damage that a few degrees of aggregate global warmth can do. Not surprisingly, it was pretty disturbing stuff, but here’s what really shocked me: one of the sponsors was Hummer!

That’s the same Hummer that is perhaps the most obscenely fat-ass gas guzzler on the (rapidly warming) planet.

I just can’t figure it out… it’s so off-the-wall that it has to be either a bizarre passive-aggressive move of some kind, or else somebody in the marketing department has figured out some crazy-like-a-fox counterintuitive trend. Maybe people who love big cars experience thrilling schadenfreude as they watch maudlin environmentalists wring their hands. Maybe wealthy eco-warriors want to buy up Hummers simply to pull them off the market. Maybe the folks at Hummer realize there’s going to be a market for environmentalists-turned-survivalist who need some horsepower to get to their compound in Montana.

The speculation is fun, but I really am baffled by this. Anybody have any theories out there?

Earthtools and Sky Clock

I added my animations to the explanation page for my Sky Clock and made a few small changes to the clock page. If you want to find your own latitude and longitude, I now link to Simon Willison’s excellent getlatlon.com.

As I was poking around for a good mapping site to find global coordinates, I came across a fun site called Earthtools.com. Earthtools is Yet Another Map Mashup, but it adds a lot of value by including such things as contour map overlays, altitude, and my favorite, sunrise and sunset times. Here’s where I work with some fun info piled on top. Last December I got a few questions about when the earliest sunset would be for location X. Now I know just where to find out.

The hazards of misanthropic environmentalism

In a magazine with the unlikely title What Is Enlightenment, I came across an excellent review of the politics of the Green movement in America. The article, A Brighter Shade of Green: Rebooting Environmentalism for the 21st Century by Ross Robertson, touches on some history and the current diversity of opinions among Greens. In the process, it gave some structure to things I’ve been puzzling over. Especially this: if it’s so easy to see that Greens are often right, why are they so damned annoying? The answer is that they hate people.

I’ll take a step back from my oversimplification and clarify. Among certain elements of the Green movement, which Robertson calls the “Dark Greens”, modern man is characterized as a disease. This is the monkey-wrenching Edward Abbey/John Muir axis of the group. It’s a seductive line of reasoning; the sins of mankind stain every corner of the globe. But you don’t have to follow the logic very far to see that the only possible solution consistent with this naturalistic world view is a horrific depopulation and a return to a primitive agrarian lifestyle among the privileged few that remain. It’s a grim prospect, unlikely to inspire anyone but the clear-eyed believers and those rich enough to afford their own guilt. The trouble is, of course, that any movement that marginalizes people must necessarily marginalize itself. Depression does not inspire.

In contrast to these Dark Greens are the so-called Bright Greens. Two exemplars of this view are Bruce Sterling and Stewart Brand. Stewart Brand is one of my heroes. Formerly of Ken Kesey’s Pranksters and the Whole Earth Review, this is a guy who could easily live in a nostalgic hippie daydream. But instead:

…as he gets older, he recently told the New York Times, he continues to become “more rational and less romantic. . . . I keep seeing the harm done by religious romanticism, the terrible conservatism of romanticism, the ingrained pessimism of romanticism. It builds in a certain immunity to the scientific frame of mind.

His investigations have led him to some surprising conclusions relative to typical Green rhetoric. For example: we need bigger cities and more nuclear power.

Regarding Dark Green guilt, I’ll close with an extended quote from Sterling:

It’s a question of tactics. Civil society does not respond at all well to moralistic scolding. There are small minority groups here and there who are perfectly aware that it is immoral to harm the lives of coming generations by massive consumption now: deep Greens, Amish, people practicing voluntary simplicity, Gandhian ashrams and so forth. These public-spirited voluntarists are not the problem. But they’re not the solution either, because most human beings won’t volunteer to live like they do. . . . However, contemporary civil society can be led anywhere that looks attractive, glamorous and seductive. The task at hand is therefore basically an act of social engineering. Society must become Green, and it must be a variety of Green that society will eagerly consume.

This makes abundant sense to me. Any fool can see that we are wrecking the planet, but we need to attack the problem with a positive attitude that has the potential to move millions. Sign me up! I’m ready to go Bright Green.

Read the whole article. It’s long but worthwhile.

Happy Groundhog Day!

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Whatever your opinion of curious ceremonies involving certain celebrated shade-bestowing rodents, I nevertheless wish you a happy Groundhog Day. Shadow or not, Spring is just over there and it’s headed this way.

Acme Rocket Boots

You know who would love YouTube? Wile E. Coyote would love YouTube.

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Take a look at the rocket boots in this video. Life imitates art. What are the odds that the Acme Company makes those little turbines? And there’s something very Coyote-like about the fact that he’s using hot water bottles for his fuel tanks.

In truth, I suppose that the coyote’s adventures are already pretty well documented on YouTube. Maybe he was the original BASE jumper.

Hey, that’s my brother!

For the last year, my oldest brother and his wife have been participating in a weekly civic protest of the war in Iraq. Up here in the Boston area, you’re unusual if you’re not protesting the war and making fun of George Bush (just ask Mitt Romney), but in a small town in red-state North Carolina, it takes considerably more courage to speak out on a topic like this. Here’s the article about it from my old hometown newspaper, the Winston-Salem Journal: Anti-war protesters join at Elkin corner every Thursday as sign of their concern. Go, bro!

I was also curious to see that the newspaper site features some video content. It’s an interesting little video clip (prominently featuring my smiling, waving brother), but more generally it’s fascinating to watch a newspaper putting up multimodal content like podcasts and video. I’m picturing someone trained as a writer being given a video camera by their editor and being told to “bring home some video.”

Two years ago, I read this interview with Dave Barry in which he talked about the predicament of the modern newspaper. They’re losing money, they’re laying off staff, and they’re telling their people to do podcasts and videos in addition to their day job. As Barry put it, “Newspapers are dead.” He told the story of how his wife, a sportswriter at the Miami Herald was asked to do a podcast for the last winter Olympics in addition to filing her normal stories. It’s hard to guess what newspapers will look like when the bleeding finally stops, but it hasn’t happened yet. I guess the same thing can be said about Iraq.

Hurricane Ivan from space

One of my new favorite sites is Riding with Robots on the High Frontier. I have always liked NASA’s Astronomy Picture of the Day, but I tend to filter out the deep space stuff. Nebula, shmebula. I want to see something in this solar system. Too many parsecs spoils the soup. Riding with Robots is dedicated to planetary probe imagery. Check out the dust devil footprints on this Martian dune.

The site also features a nifty Planet Portal that shows active missions. You get a sense of news, without the over-the-top treatment at Space.com. I’ve always wanted to open up a space mission-themed sports bar. Instead of hockey on this TV and football on that one, you’d have Jupiter on this TV and Mars on that one, with crowds of Zima-swilling geeks elbowing each other for a look at the action. But help me out here: what should I call it?

I can’t remember where I first saw this image of Hurricane Ivan as viewed from the space station. It was probably on APOD. It’s an arresting image, and it struck me as a picture taken from the ground looking up past a tall building at some bizarre atmospheric disturbance.

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I couldn’t shake the feeling that I had seen that image somewhere before. Then I remembered I had been playing the game Half Life, which prominently features this image.

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The artists for this game had to be working from this image, right? The similarities are remarkable.

Color My World

Which word is more colorful: color or colour?

If you’re American, do you ever color your “colors” with an occasional “U” to lend your prose a sense of savoir faire? At any rate, have you ever wondered where the U went? A lovely blog called COLOURlovers addresses this question with an informative post called Color vs. Colour – The Great Spelling Battle. The short version is that when Noah “Dictionary is My Last Name” Webster saw colour he saw red. If you know what I mean.

By the way, from the COLOURlovers site, I also recommend the Color Legends posts (Part I and Part II).

When it comes to teasing apart the idiomatic weirdness of language, no one is better than Rambles contributor Alan Kennedy. So we are tickled pink this week to have Alan tell us about the strangely liberal and incoherent use of color across cultures. Take it away Alan…

Continue reading “Color My World”